Selectins modify dendritic cells during atherosclerosis
نویسندگان
چکیده
منابع مشابه
Plasmacytoid Dendritic Cells in Atherosclerosis
Atherosclerosis, a chronic inflammatory disease of the vessel wall and the underlying cause of cardiovascular disease, is initiated and maintained by innate and adaptive immunity. Accumulating evidence suggests an important contribution of autoimmune responses to this disease. Plasmacytoid dendritic cells (pDCs), a specialized cell type known to produce large amounts of type I interferons (IFNs...
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Atherosclerosis is the number one cause of death in the Western world. It results from the interaction between modified lipoproteins and cells such as macrophages, dendritic cells (DCs), T cells, and other cellular elements present in the arterial wall. This inflammatory process can ultimately lead to the development of complex lesions, or plaques, that protrude into the arterial lumen. Ultimat...
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ژورنال
عنوان ژورنال: Chronic Diseases and Translational Medicine
سال: 2018
ISSN: 2095-882X
DOI: 10.1016/j.cdtm.2018.03.001